| TABLE 8.
Differentiating viral and alcoholic hepatitis |
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| Viral hepatitis | Alcoholic hepatitis | |
| History | Risk factors | Significant alcoholic intake |
| Physical examination | Mild hepatomegaly, extrahepatic stigmata not prominent | Moderate to marked hepatomegaly, florid stigmata |
| Laboratory examination | AST variable ALT > AST |
AST <300 AST > ALT (often 2:1 or more) |
| Liver biopsy | Mononuclear cells Portal tract centered Ground glass cells (HBV) Special stains (HBV) |
Polymorphs Pericentral, diffuse Mallory's hyaline Fat |