TABLE 4.   Interpretation of hepatitis B markers
Marker Interpretation

HBsAg Active HBV infection; may be acute or chronic
HBsAb Immune to HBV; may be natural immunity or following vaccination
HBcAb-IgM Acute HBV infection (newer and more sensitive assays may also be positive during reactivation of chronic infections)
HBeAg High infectivity, active viral replication
HBeAb Low or no infectivity; need only be measured in chronic HBV
HBV-DNA Direct measure of infectivity or replicative state; becoming increasingly available