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ISCHEMIC DISEASE OF THE
INTESTINE
P.H. MacDonald and I.T. Beck
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page
263 |
1. Introduction
Intestinal
ischemia occurs when, as a result of inadequate systemic blood flow or
local vascular abnormalities, the metabolic demand of the tissue
supersedes the delivery of oxygen. In older patients inadequate vascular
supply is frequent, and thus ischemic bowel disease occurs most often in
the elderly. It may also be seen in young patients suffering from vascular
abnormalities - e.g., collagen diseases, vasculitis, diabetes - or in
those taking vasoconstrictor drugs. Clinical manifestations are varied,
depending on the site of the vascular occlusion and the extent of the
bowel necrosis. |