TABLE 8.   Differentiating viral and alcoholic hepatitis
Viral hepatitis Alcoholic hepatitis

History Risk factors Significant alcoholic intake
Physical examination Mild hepatomegaly, extrahepatic stigmata not prominent Moderate to marked hepatomegaly, florid stigmata
Laboratory examination AST variable
ALT > AST
AST <300
AST > ALT (often 2:1 or more)
Liver biopsy Mononuclear cells
Portal tract centered
Ground glass cells (HBV)
Special stains (HBV)
Polymorphs
Pericentral, diffuse
Mallory's hyaline
Fat