TABLE 13.   Comparison of PBC and PSC
	PBC	PSC
Symptoms	Often none/pruritus	Often none
Biochemistry	Elevated ALP	Elevated ALP
Serum bilirubin	Slow rise	Fluctuates
Non-organ specific Ab	AMA+ve	AMA-ve
Liver histology	Helpful in diagnosis/staging	Helpful in staging
ERCP	Normal	Abnormal